You may need to have a dental exam before you begin treatment with Prolia. Your doctor may have you take extra calcium and vitamin D while you are being treated with denosumab. Take only the amount of calcium and vitamin D that your doctor has prescribed.
- Aromatase inhibitors are a class of drugs that are often used for adjuvant treatment of breast cancer.
- If you have serious side effects from Prolia, call your doctor right away.
- However, drinking too much alcohol may raise your risk of falling.
Advise patients to seek prompt medical attention if they develop signs or symptoms of severe infection, including cellulitis. When an organization includes certain drugs in treatment guidelines, this means that research has shown the drug to be safe and effective. Evenity and Prolia are included in guidelines from the Endocrine Society. The guidelines recommend either drug as a treatment option for certain females who have gone through menopause and are at high risk of bone fractures.
Examples of bisphosphonate drugs are Fosamax (alendronate) and Actonel (risedronate). Prolia comes with a warning about a low level of calcium in the blood. If you have a low calcium level, you should not take Prolia. Your doctor will order blood tests to check your level before you start using Prolia and regularly during your treatment. While you’re receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. If your levels are high, they’ll typically recommend lifestyle changes and medication.
During Prolia® treatment, patients should be advised to report new or unusualthigh, hip, or groin pain. Any patient who presents with thigh or groin pain should beevaluated to rule out an incomplete femur fracture. Interruption of Prolia®therapy should be considered, pending a risk/benefit assessment, on an individual basis. For patients requiring invasive dental procedures, clinical judgment should guide themanagement plan of each patient. Patients who are suspected of having or who develop ONJshould receive care by a dentist or an oral surgeon.
Your doctor will determine if giving yourself injections at home is right for you. You can keep taking Prolia for as many years as your doctor recommends. Studies of the drug were done over a 3-year period, but it can be used for longer periods of time. It’s given as an injection under your skin by your doctor. They’ll inject Prolia under the skin of your belly, upper arm, or upper thigh. This section covers common questions about the dosage of Prolia.
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Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. This drug may decrease your body’s ability to fight infection. Inform patients that severe bone, joint, and/or muscle pain have been reported in patients taking Prolia. Patients should report severe symptoms if they develop [see WARNINGS AND PRECAUTIONS]. During Prolia treatment, patients should be advised to report new or unusual thigh, hip, or groin pain. Any patient who presents with thigh or groin pain should be suspected of having an atypical fracture and should be evaluated to rule out an incomplete femur fracture.
The most common adverse reactions reported with Prolia in patients with glucocorticoid-induced osteoporosis are back pain, hypertension, bronchitis, and headache. Some people may have a higher risk of certain side can microdosing mushrooms reduce anxiety depression and stress effects from Evenity or Prolia. For example, having certain medical conditions can raise your risk of side effects from either medication. To learn more, see the “What are the warnings for Evenity and Prolia?
Drug details
Another trial compared Prolia to a drug called risedronate. This trial looked at treating osteoporosis caused by certain corticosteroids. In this trial, 3.8% of people taking Prolia reported skin side effects, such as a rash. In comparison, 4.2% of people taking risedronate reported skin side effects. If you have hip pain while you’re taking Prolia, it’s important that you talk with your doctor right away.
Alcohol and Prolia
(This is especially true if the supplements are taken long term.) In some cases, the benefit of taking calcium and vitamin D supplements may outweigh the risk of kidney stones. No, mixing alcohol and percocet in clinical trials of Prolia there weren’t any eye-related side effects reported. However, certain other medications used to treat osteoporosis may cause eye-related side effects.
How long can I take Prolia?
After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk of breaking bones, including bones in your spine, is increased. Your risk of having more than 1 broken bone in your spine is increased if you have already had a broken bone in your spine. Do not stop, skip, or delay taking Prolia without first talking with your doctor. If your Prolia treatment is stopped, talk to your doctor about other medicines that you can take.
